iss070e002586 (Oct. 7, 2023) — Southern Italy (to the right of the image) meets Sicily (to the left), the largest island in the Mediterranean Sea and one of 20 Italian regions. At its closest point, Sicily resides only 2 miles (~3.2km) from mainland, the two connected by the Strait of Messina. From 260 miles above, the International Space Station offers a unique vantage point of where the two regions meet.